single faculty member

  • Dr.

    Paula Belinsky
  • Senior Lecturer

  • Food Sciences - B.Sc. Program
  • 00-972-55-6642014, 00-54-3424090028
  • paudabe@gmail.com
    • Nutrition
    • Agriculture
    • Biochemistry
  • •    Lignin peroxidase expression in the white rot fungus Phanerochaete chrysosporium – Characterization of the mechanism of lignin peroxidase production by the fungus. Connection of the production to oxidative stress, reactive oxygen species, and antioxidant enzymes. Relation to signal transduction pathway.
    •    Heterologous expression of lignin peroxidase in the yeast Pichia pastoris – Optimization of culture conditions for overproduction of the recombinant enzyme and structural and activity comparison between the enzyme expressed by P. pastoris and the enzyme produced by P. chrysosporium 
    •    Large scale lignin peroxidase production – Development and scale up for production of lignin peroxidase by different white rot fungi. Scale up of downstream process. Optimization of spore production at large quantities.
    •    Development of formulations containing lignin peroxidase for skin whitening – Test of compatibility of the different formula components with the enzyme. Determination of optimal melanin oxidation by lignin peroxidase formulation.

     

  • •    General and Inorganic Chemistry 
    •    Antioxidants in Food and Medicine
    •    Advance course in bioreactors and Fermentation (M.Sc. studies in Biotechnology)
    •    Food sciences seminar

     

  • Full CV download
  • •    Gordon Research Conferences. Cellular & Molecular Fungal Biology. Holderness, New Hamshire, USA. Matityahu, A.; Belinky, P. A. Involvement of protein kinase C in lignin peroxidase expression in oxygenated cultures of the white rot fungus Phanerochaete chrysosporium. Poster presentation.
    •    9th European Conference on Fungal Genetics University of Edinburgh, Scotland. Matityahu, A.; Hadar, Y.; Belinky, P. A. Gene Silencing by RNA Interference in the White Rot Fungus Phanerochaete chrysosporium. Poster presentation.
    •    The 5th Congress of the Federation of Israel Societies for Experimental Biology, Eilat, Israel. Matityahu, A.; Belinky, P. A. The role of ROS and MnSOD in the induction of Lignin Peroxidase in Phanerochaete chrysosporium. Poster presentation.
    •    23rd Annual Meeting of the Israel Society for oxygen and free radical research. Tel Aviv University, Israel. Matityahu, A.; Belinky, P. A. Induction of Lignin Peroxidase in Phanerochaete chrysosporium. Poster presentation.
    •    23rd Annual Meeting of the Israel Society for oxygen and free radical research. Tel Aviv University, Israel. Cohen, S.; Belinky, P.A. Oxidation of Catechols by Lignin Peroxidase. Poster presentation. 
    •    22nd Annual Meeting of the Israel Society for oxygen and free radical research. Tel Aviv University, Israel. Matityahu, A.; Belinky, P.A. Reactive Oxygen Species and Induction of Lignin Peroxidase in Phanerochaete chrysosporium. Poster presentation. 
    •    The 4th Congress of the Federation of Israel Societies for Experimental Biology, Eilat, Israel. Matitiahu, A.; Belinky, P.A. Reactive Oxygen Species and Induction of Lignin Peroxidase in Phanerochaete chrysosporium. Poster presentation. Cohen, S.; Belinky, P.A. Oxidation of Catechol by lignin peroxidase. Poster presentation. 
    •    Society for free radical research SFRR-Europe meeting 2003: “Free radicals and Oxidative Stress: Chemistry Biochemistry and Pathophysiological implications”, Ioannina, Greece. Belinky, P.A.; N. Flikshtein, N.;  Lechenko, S.; Gepstein, S and Dosoretz, C.G. Involvement of Reactive Oxygen Species in the induction of lignin peroxidase gene expression in liquid cultures of Phanerochaete chrysosporium. Lecture.
    •    Annual meeting of the Israel Society of Microbiology, Hebrew University, Jerusalem, Israel. Flikshtein, N.; Belinky, P.A;  Lechenko, S.; Gepstein, S and Dosoretz, C.G. Effect of molecular oxygen in liquid cultures of Phanerochaete chrysosporium. Poster presentation.
    •    The 3rd Congress of the Federation of Israel Societies for Experimental Biology, Eilat, Israel. Belinky, P.A.; N. Flikshtein, N.; Lechenko, S.; Gepstein, S and Dosoretz, C.G. Effect of molecular oxygen in liquid cultures of Phanerochaete chrysosporium. Poster presentation.
    •    Meeting of the Society for Research, Prevention and Treatment of Atherosclerosis, Ashkelon, Israel. Mahmood, S.; Belinky, P. A.; Tamir, Snait; Vaya, J. Quantum Chemical Computation of glabridin in relation to its inhibitory effect on LDL oxidation. Poster presentation.
    •    The 70th meeting of the European Atherosclerosis Society, Geneve, Switzerland. Belinky, P. A.; Aviram, M.; Mahmood, S.; Vaya, J. Structural aspects of the inhibitory effect of glabridin on LDL oxidation.  Poster presentation.
    •    The first Regional Meeting on Medical Sciences: The Role of Free Radicals in Health and Disease, Jerusalem and Amman, Jordan. Belinky, P. A.; Aviram, M.; Mahmood, S.; Vaya, J. Structural aspects of the inhibitory effect of glabridin on LDL oxidation. Poster presentation. 
    •    The 4th Annual Meeting of the Society for Research, Prevention and Treatment of Atherosclerosis, Eilat, Israel. Belinky, P. A.; Aviram, M.; Fuhrman, B.; Rosenblat, M.; Vaya, J. The antioxidative effects of the isoflavan glabridin on endogenous constituents of LDL during its oxidation. Poster presentation.
    •    The Annual Meeting of the Israeli Society of Free Radicals, Bar Ilan University, Israel. Belinky, P. A.; Aviram, M.; Fuhrman, B.; Rosenblat, M.; Vaya, J. The antioxidative effects of the isoflavan glabridin on endogenous constituents of LDL during its oxidation. Lecture.